王宇凡,李咏梅

创伤性脑损伤后继发性损伤严重影响患者预后，炎症反应是其中的关键病理机制。本文系统阐述了炎症反应在TBI继发性损伤中的作用机制，包括小胶质细胞激活、促炎因子释放、血脑屏障破坏及氧化应激等环节，为后续针对性治疗提供依据。

创伤性脑损伤；炎症反应；继发性损伤；小胶质细胞

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