With the continuous advancement of mobile communication technology, the emerging operating system HarmonyOS has a promising future in the field of mobile application development. This study mainly focuses on the  innovation of teaching model integrating HarmonyOS into the mobile application development courses in colleges and universities, carefully analyzes the problems in the current teaching system, and provides some systematic improvement plans from the improvement of course content, the update of teaching methods, the establishment of practice platforms, and the cultivation of teaching staff to train application-oriented compound talents who have both HarmonyOS development capabilities and innovative ability, promote the integration of higher education with industry needs, and propel the HarmonyOS ecosystem towards sustainable development through these reform measures.

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