袁 英,管利荣

肺部超声（Lung Ultrasound, LUS）作为一种无创、无辐射的影像学技术，近年来在新生儿肺部疾病的诊断和治疗中展现出显著的优势。新生儿肺部疾病如呼吸窘迫综合征、肺炎和气胸等，因其高发病率和潜在严重性，亟需快速、准确的诊断方法。传统影像学技术虽应用广泛，但存在辐射暴露和操作复杂等问题。相比之下，LUS具有操作简便、可床旁实时监测及无辐射等优势，逐渐成为新生儿肺部疾病的重要诊断工具。本文总结了LUS在新生儿常见肺部疾病中的应用进展，并展望其在临床实践中的推广前景及未来研究方向。

肺部超声；新生儿；呼吸窘迫综合征；肺炎；气胸；诊断

[1] Possmayer F, Veldhuizen RAW, Jobe AH. Reflections on the introduction of surfactant therapy for neonates with respiratory distress. Am J Physiol Lung Cell Mol Physiol. 2025 Apr 1;328(4):L554-L563. doi: 10.1152/ajplung.00355.2024. Epub 2025 Feb 14. PMID: 39951688. [2] Huang P, Chen D, Liu X, Zhang X, Song X. Diagnostic value of bedside lung ultrasound and 12-zone score in the 65 cases of neonatal respiratory distress syndrome and its severity. Biomed Eng Online. 2024 Mar 6;23(1):29. doi: 10.1186/s12938-024-01224-0. PMID: 38448872; PMCID: PMC10918994. [3] Du T, Lei H, Dong J, Wang Y, Li J. Clinical evaluation of serum miR-513a-3p combined with arterial blood gas analysis parameters and lung ultrasound score in neonatal respiratory distress syndrome. Ital J Pediatr. 2024 Oct 29;50(1):227. doi: 10.1186/s13052-024-01795-7. PMID: 39472946; PMCID: PMC11523833. [4] Zhang Z, Guo L, Wang H, Zhang Z, Shen L, Zhao H. Diagnostic accuracy of lung ultrasound to predict weaning outcome: a systematic review and meta-analysis. Front Med (Lausanne). 2024 Nov 1;11:1486636. doi: 10.3389/fmed.2024.1486636. PMID: 39554497; PMCID: PMC11563988. [5] Raimondi F, Rodriguez Fanjul J, Aversa S, Chirico G, Yousef N, De Luca D, Corsini I, Dani C, Grappone L, Orfeo L, Migliaro F, Vallone G, Capasso L; Lung Ultrasound in the Crashing Infant (LUCI) Protocol Study Group. Lung Ultrasound for Diagnosing Pneumothorax in the Critically Ill Neonate. J Pediatr. 2016 Aug;175:74-78.e1. doi: 10.1016/j.jpeds.2016.04.018. Epub 2016 May 14. PMID: 27189678.

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