秦丽媛

目的：探寻理想的慢性咳嗽治疗方案，分析从阴虚论治三参二梗汤治疗的效果。方法：2023.7-2024.10，以医院收治的60例慢性咳嗽患者为观察对象，经随机抽签法分组，对照组30例采用西医常规治疗、观察组30例三参二梗汤（阴虚论治方剂）治疗。结果：治疗后对比两组中医证候积分、炎症因子水平、治疗总有效率，差异有统计学意义（P＜0.05）。结论：慢性咳嗽患者采用三参二梗汤治疗，可有效改善症状体征，抑制炎症因子释放，提高临床治疗效果。

三参二梗汤；慢性咳嗽；中医证候积分；炎症因子；治疗总有效率；西医

[1] MORICE,ALYN H.,BIRRING,SURINDER S.,SMITH,JACLYN A.,et al.Characterization of Patients With Refractory or Unexplained Chronic Cough Participating in a Phase 2 Clinical Trial of the P2X3-Receptor Antagonist Gefapixant[J].Lung.,2021,199(2):121-129. [2] RIBEIRO,VANESSA VEIS,CASMERIDES,MARIA CHRISTINA BUSSAMARA,REIS,ZELIA MARIA CONCEICAO DA SILVA,et al.Efficacy of Speech-language Pathology Therapy in Chronic Cough:Systematic Review With Meta analysis[J].Journal of voice:official journal of the Voice Foundation,2024,38(3):674-682. [3] 黄金凤.苓甘五味姜辛汤联合止咳散治疗慢性咳嗽伴睡眠障碍的疗效及对患者症状改善及睡眠质量的影响[J].世界睡眠医学杂志,2022,9(3):426-428. [4] SKAABY,STINNA,FLACHS,ESBEN MEULENGRACHT,LANGE,PETER,et al.Chronic productive cough and inhalant occupational exposure-a study of the general population[J].International archives of occupational and environmental health:Internationales Archiv fur Arbeits-und Umweltmedizin,2021,94(5):1033-1040. [5] ABDULQAWI,RAYID,SATIA,IMRAN,KANEMITSU,YOSHIHIRO,et al.A Randomized Controlled Trial to Assess the Effect of Lidocaine Administered via Throat Spray and Nebulization in Patients with Refractory Chronic Cough[J].The journal of allergy and clinical immunology.In practice.,2021,9(4):1640-1647. [6] AKIO NIIMI,HIRONORI SAGARA,MASASHI KIKUCHI,et al.A phase 3,randomized,double-blind,clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough[J].Allergology international:official journal of the Japanese Society of Allergology,2022,71(4):498-504. [7] 郭芬芳,武青.麻杏二三汤加减联合推拿治疗儿童慢性咳嗽痰湿阻肺证的疗效及对患儿肺功能、炎症因子水平的影响[J].海南医学,2022,33(8):1024-1026. [8] 李晓娣,谢佳佳,王明选,等.参芪补肺汤联合孟鲁司特钠片治疗非小细胞肺癌术后慢性咳嗽的临床研究[J].河北中医,2024,46(8):1292-1296. [9] 刘海军,王明选,谢佳佳,等.参芪补肺汤加减联合孟鲁司特钠治疗非小细胞肺癌术后慢性咳嗽的临床研究[J].中国医院用药评价与分析,2023,23(8):959-962. [10] 谢佳佳,王明选,王春微,等.参芪补肺汤加减治疗老年非小细胞肺癌根治术后慢性咳嗽的临床分析[J].老年医学与保健,2023,29(3):469-474. [11] 于峰伟,刘建东,王婷婷.清热宣肺解毒汤联合孟鲁司特治疗小儿支原体肺炎后慢性咳嗽的疗效观察[J].天津中医药,2023,40(9):1101-1105. [12] 张萍萍,韩一恒,李伟伟.生脉散合温胆汤化裁治疗小儿慢性咳嗽及对其免疫力及炎性因子水平的影响[J].中医药学报,2024,52(10):67-71. [13] 赵一粒,拓晓萍.宣肺运脾汤治疗儿童慢性咳嗽(痰湿蕴肺型)的疗效及对患儿炎症因子、免疫功能的影响[J].海南医学,2022,33(12):1559-1562. [14] 黄鹤,关艳楠,张晓霞.润肺平喘汤对肺脾气虚型慢性咳嗽患儿临床疗效、肺功能及免疫功能的影响[J].中国医学创新,2023,20(13):86-89. [15] 方俊成,黎业鹏,王志伟.三参二梗汤联合西药治疗气阴两虚型慢性咳嗽的临床效果观察[J].中国中医药科技,2021,28(1):145-147.

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