李 雨,张家勤,左艳芳

目的：探讨儿童哮喘患儿呼出气一氧化氮（FeNO）水平分布特点及其与儿童哮喘控制状态的关系。方法：回顾性纳入儿童哮喘患儿361例，根据FeNO水平分为<25 ppb、25-50 ppb及≥50 ppb三组，依据GINA标准评价哮喘控制状态，并进行年龄分层分析。结果：本研究共纳入361例患儿，不同性别患儿FeNO水平分布无统计学差异（x2=0.68，P=0.710）；哮喘控制状态与FeNO水平分布相关（x2=15.27，P=0.004），哮喘控制不佳患儿高水平FeNO占比更高；10-14岁患儿FeNO水平分布与5-9岁患儿存在统计学差异（x2=23.25，P<0.001）。结论：本研究数据提示FeNO水平高低与哮喘控制程度存在相关性，临床中可将FeNO检测作为评估患儿气道炎症状态的辅助参考指标。

儿童哮喘；呼出气一氧化氮；气道炎症；哮喘控制

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