作者
王 帅,杨寒冰,邵 玥,严东语,春 花
文章摘要
目的:比较高海拔地区肝癌患者腹腔镜手术与开腹手术的疗效,探讨SpO2及术前肺部合并症对恢复的影响。方法:回顾性分析2023—2025年西藏某院肝切除64例(腹腔镜33例、开腹31例),记录术后24 h最低SpO2,<90%为低氧,分析术前肺部合并症对预后的影响。结果:腹腔镜出血更少、住院更短。低氧者住院时间延长(16 d vs 12 d)。高原本身降低SpO2,合并慢阻肺、肺气肿等术前肺部基础病者SpO2更低、预后更差。结论:高海拔肝切除中腹腔镜更利于康复;术后早期SpO2及术前肺部合并症是重要预后因素。
文章关键词
肝细胞癌;腹腔镜手术;开腹手术;SpO2;影响因素
参考文献
[1] 程远,徐子令,荚卫东.肝细胞癌转化治疗临床策略与指南解读[J].肝胆外科杂志,2023,31(01):16-19.
[2] 王永泽,李孝敏.腹腔镜肝切除术与开放式肝切除术治疗肝细胞癌的近期疗效对比[J].中国临床研究,2024,37(06):876-879.
[3] S.W G-C,Gabriela S-T.High altitude and cancer:An old controversy[J].Respiratory Physiology&Neurobiology,2021,289103655-103655.
[4] Lei R,Gu M,Li J,et al.Lipoic acid/trometamol assembled hydrogel as injectable bandage for hypoxic wound healing at high altitude[J]. Chemical Engineering Journal,2024,489151499-.
[5] SeongA J,MoonWon Y,InSeob L,et al.Comparing surgical and oncologic outcomes between laparoscopic gastrectomy and open gastrectomy in advanced gastric cancer with serosal invasion:A retrospective study with propensity score matching.[J].European journal of surgical oncology:the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology,2022, 48(9):1988-1993.
[6] 赵春华,张小伟,任玉芝.危重症患者院内安全转运发生血氧饱和度降低的影响因素分析[J].齐鲁护理杂志,2021,27(15):140-142.
[7] Simon S,Gottlieb J,Burchert I,et al.Outcomes and Functional Deterioration in Hospital Admissions with Acute Hypoxemia.[J].Advances in respiratory medicine,2024,92(2):145-155.
[8] Wang J,Ren D,Liu Y,et al.Effects of early mobilization on the prognosis of critically ill patients:A systematic review and meta- analysis[J].International Journal of Nursing Studies,2020,110103708-103708.
[9] 王松,刘建,刘彦立.腹腔镜肝切除术治疗小肝癌的中远期疗效及对患者外周血T淋巴细胞亚群的影响[J].实用癌症杂志,2024, 39(03):462-465+469.
[10] 范明,杨龙,金亮,等.不同入肝血流阻断技术下腹腔镜肝切除术治疗原发性肝癌患者近期效果研究[J].实用肝脏病杂志,2024, 27(01):101-104.
[11] Poornima S,Swaraj M,Yasmin A.A study of survival strategies for improving acclimatization of lowlanders at high-altitude.[J].Heliyon, 2023,9(4):e14929-e14929.
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