王泰棋,姚 月,戚孟春

本文综述讨论了牙釉质基质蛋白（EMP）和其衍生物（EMD）在口腔领域的作用与证据。总体来看，EMD可促进获得牙周附着和减小牙周袋深，并且其与牙周组织再生还存在着一定的的联系。机制上看，EMD兼具促血管生成、促成纤维细胞/成骨相关分化与早期炎症控制等相关效应。在牙体牙髓与正畸根吸收和种植软组织管理等场景中EMD亦显示出协同或潜在应用价值。综合来看，EMD在口腔中多学科多学科领域有着不错的可发展前景。

釉基质蛋白；Emdogain；再生；根吸收

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