刘宇佳,李玉英

目的：明确相对脂肪量（Relative Fat Mass，RFM）与成人肺功能指标之间的关联。方法：采用美国国家健康与营养调查（NHANES）2007-2012年的横断面数据，纳入5615名20-64岁符合标准的参与者。通过多变量线性回归模型分析RFM与用力肺活量（FVC）、一秒用力呼气容积（FEV1）、峰值呼气流速（PEF）、25%-75%用力呼气流速（FEF25%-75%）及FEV1/FVC比值的相关性；运用平滑曲线拟合和阈值效应分析探索潜在非线性关系。结果：完全校正模型显示，RFM每增加1个单位，FVC、FEV1、PEF分别显著下降0.17 L（95%CI：-0.21~-0.13）、0.11 L（95%CI：-0.14~-0.08）和0.20 L/s（95%CI：-0.29~-0.11）（均P<0.001），而RFM与FEF25%-75%无显著相关性（P=0.645）。阈值效应分析发现，RFM与FEV1/FVC存在非线性关联（P非线性=0.9738），拐点为22.1043；当RFM<22.1043时，FEV1/FVC随RFM增加显著下降（β=-0.0046，95%CI：-0.0064~-0.0028），RFM>22.1043时呈微弱正相关但无统计学意义（β=0.0009，95%CI：0.0001~0.0017）。结论：较高的RFM与成人肺功能（FVC、FEV1、PEF）下降风险呈正相关，且存在阈值效应。

相对脂肪量；肺功能；肥胖症

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