吴博婷,简生燕

尿酸（Uric acid，UA）作为嘌呤代谢的最终产物，在生理水平浓度下对健康起着积极作用，包括抗氧化、增强免疫及抗衰老等功能，当尿酸在体内过度蓄积进一步造成高尿酸血症。研究表明高尿酸通过氧化应激、炎症反应及线粒体功能障碍等机制参与多囊卵巢综合征（Polycystic ovary syndrome，PCOS）、子宫内膜异位症、肥胖及胰岛素抵抗（Insulin resistance，IR）等疾病的发生发展。本文就高尿酸在女性生殖系统疾病中的研究进行综述，以期为今后的研究提供一定的依据。

尿酸；多囊卵巢综合征；肥胖；胰岛素抵抗；女性不孕症

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