张家豪,林蓉香,张嘉璇

维生素Ｄ是机体不可或缺的维生素，在各个生理过程中都起着重要作用，参与调节体内钙磷代谢的同时，还可影响人体自身免疫、凝血、组织炎症和细胞活性。它分布广泛，在人类有核细胞中普遍表达，其水平受着年龄、性别、光照、激素等多种因素的影响。心房颤动（AF），心律失常中最常见的类型之一，其所带来的主要危害之一是血栓形成脱落导致的卒中风险，各种研究表示促进房颤产生的机制很多，但是到目前为止房颤的形成机制仍不明确，近年研究发现，维生素D与心力衰竭、高血压、冠心病、心肌病、心律失常等多种心血管疾病的发生、发展密切相关。本文主要就维生素D及其水平在房颤发病机制中的作用的最新研究进展做一综述。

维生素D；房颤；RAAS；炎症因子；肥胖

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