作者
毛 倩,吴晶晶,刘长菊,闵 霞
文章摘要
目的:探讨瞬感动态血糖监测系统(CGMS)在急性胰腺炎(AP)患者血糖管理中的临床价值。方法:本研究为回顾性队列研究。采用随机数字表法将2023年3月至2024年3月在南京医科大学附属江宁医院收治的70例急性胰腺炎患者随机分为实验组和观察组,每组35例。对照组采用指尖血糖监测方式(POCT),观察组采用瞬感动态血糖监测系统(CGMS)进行血糖管理。主要观察指标包括:平均血糖(MBG)、血糖变异系数(CV)、血糖达标时间(Time in Range,TIR)、低血糖次数、胰岛素使用量、感染发生率、住院时间、肠功能恢复时间等。所有数据通过Shapiro-Wilk正态性检验,正态分布数据采用独立样本t检验,非正态分布数据使用Mann-Whitney U检验,分类变量采用X2检验(当理论频数<5时使用Fisher精确检验)。结果:与对照组相比,观察组患者的MBG显著降低(7.9±1.3 vs.9.1±1.4 mmol/L,P<0.01),CV值明显下降(21.4%vs.28.7%,P<0.05),TIR显著提高(74.2%vs.61.3%,P<0.01),低血糖事件次数更少(0.26 vs.1.12次/人,P<0.01)。此外,观察组住院时间、肠功能恢复时间、感染发生率及胰岛素使用总量均较对照组更低,差异具有统计学意义(P<0.05)。结论:瞬感动态血糖监测系统在AP患者血糖管理中具有更高的敏感性与安全性,能更精准地识别高/低血糖波动,降低并发症发生率,缩短住院时间,值得临床推广。
文章关键词
急性胰腺炎;动态血糖监测;CGMS;血糖变异性;感染率
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