郭林呓,王正想

银屑病是一种常见的慢性炎症性皮肤病，其复杂的发病机制涉及众多免疫细胞和细胞因子及其相互作用。它极大程度上降低了患者的生活质量。近年来，在对银屑病发病过程的研究中，干扰素-α（IFN-α）作为一种重要的细胞因子受到广泛关注。研究表明，IFN-α能够调节免疫细胞的功能，影响炎症反应的程度，并与其他细胞因子相互作用，是银屑病发生与发展过程中关键的一环，从而成为值得研究的重要因子。然而，目前对IFN-α在银屑病发病机制中的具体作用及其机制仍不够明确。本文旨在综述现有文献、总结IFN-α在银屑病中的最新研究进展、探讨其在银屑病治疗中的潜在应用，同时指出未来研究的方向，以期为深入理解银屑病的发病机制提供全新的视角。

银屑病；IFN-α；发病机制；免疫反应；炎症

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