陈海岳,贺 元,朱 斌,雷登强,关炳瑜

全脊柱内镜辅助下腰椎融合术（Endoscopic Lumbar Interbody Fusion，Endo-LIF）是微创脊柱外科领域的革命性进展，将内镜精准可视化优势与传统融合技术结合。本综述系统阐述Endo-LIF技术分类（Endo-PLIF、Endo-TLIF、Endo-OLIF）、核心操作要点、适应症拓展（腰椎间盘突出症伴不稳、退变性滑脱I-II度、椎管狭窄、腰椎术后失败综合征等）、临床疗效（VAS、ODI显著改善率>70%，平均融合率>90%）、并发症管理（神经损伤<5%，硬膜撕裂<8%）及其独特优势（出血量<50ml，住院时间<4天）。证据表明，Endo-LIF在精准减压、保留脊柱稳定性结构、加速康复方面优势显著。然而，陡峭学习曲线、镜下融合操作难度、长期随访数据待完善等问题仍需关注。未来发展方向包括器械智能化（机器人/导航整合）、生物材料创新（3D打印融合器）、操作标准化及扩大适应症探索（退变性侧弯、OLIF翻修）。

全脊柱内镜；内镜腰椎融合术；Endo-LIF；微创脊柱外科；腰椎退变性疾病；并发症

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