余承栋,李桂芳

本文综述了近年来早产儿肠内营养的研究进展。通过分析现有文献，就早产儿住院期间肠内营养乳品的选择、母乳强化剂的适用人群、奶量增长时机及速度、喂养方式进行了介绍。同时，对于早产儿出院后的远期生长发育情况，我们需要做出更多的随访及研究。

早产儿；肠内营养；喂养

[1] Thoene M,Anderson-Berry A.Early Enteral Feeding in Preterm Infants:A Narrative Review of the Nutritional,Metabolic,and Developmental Benefits.Nutrients.2021 Jul 1;13(7):2289. [2] Hair AB,Scottoline B,Good M.Dilemmas in human milk fortification.J Perinatol.2023 Jan;43(1):103-107. [3] Miller J,Tonkin E,Damarell RA,et al.Collins CT.A Systematic Review and Meta-Analysis of Human Milk Feeding and Morbidity in Very Low Birth Weight Infants.Nutrients.2018 May 31;10(6):707. [4] Lapidaire W,Lucas A,Clayden JD,et al.Human milk feeding and cognitive outcome in preterm infants:the role of infection and NEC reduction.Pediatr Res.2022 Apr;91(5):1207-1214. [5] Cartagena D,Penny F,McGrath JM,et al.Differences in Neonatal Outcomes Among Premature Infants Exposed to Mother's Own Milk Versus Donor Human Milk.Adv Neonatal Care.2022 Dec 1;22(6):539-549. [6] 林新祝,李正红,常艳美,等.早产儿肠内营养管理专家共识（2024年）[J].中国当代儿科杂志,2024,26(06):541-552. [7] Muts J,van Keulen BJ,van Goudoever JB,et al.Formula protein versus human milk protein and the effects on growth in preterm born infants.Curr Opin Clin Nutr Metab Care.2025 Jan 1;28(1):33-38. [8] Embleton ND,Jennifer Moltu S,Lapillonne A,et al.Enteral Nutrition in Preterm Infants(2022):A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts.J Pediatr Gastroenterol Nutr.2023 Feb 1;76(2):248-268. [9] Oddie SJ,Young L,McGuire W.Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants.Cochrane Database Syst Rev.2021 Aug 24;8(8):CD001241. [10] Quigley M,Embleton ND,McGuire W.Formula versus donor breast milk for feeding preterm or low birth weight infants.Cochrane Database Syst Rev.2019 Jul 19;7(7):CD002971. [11] Sadrudin Premji S,Chessell L,Stewart F.Continuous nasogastric milk feeding versus intermittent bolus milk feeding for preterm infants less than 1500 grams.Cochrane Database Syst Rev.2021 Jun 24;6(6):CD001819.

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