张雨龙,王 聪

原发性肝细胞癌（HCC）是全球范围内一种高发且致死率高的恶性肿瘤，早期诊断和治疗对于提高患者生存率至关重要。然而，HCC早期常缺乏特异性临床症状，导致早期诊断困难。目前临床上依赖影像学检查结合实验室指标进行诊断，但影像学检查存在一定的局限性，如费用高、辐射损伤等，且部分早期HCC病灶难以检出。因此，寻找灵敏度和特异性更高的实验室指标，并优化其在HCC诊断中的应用策略，具有重要的临床意义。深入探讨不同实验室指标的诊断性能，及其联合应用的价值，可以帮助临床医生更准确地评估HCC风险，制定更有效的治疗方案，并为未来的HCC诊断技术研发提供理论依据和方向。

原发性肝细胞癌；实验室指标；诊断价值；研究进展

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