高度近视眼内结构形态学变化及相关性分析

ISSN:2705-098X(P)

EISSN:2705-0505(O)

语言:中文

作者
陈 晨,贾 晶
文章摘要
目的:探讨高度近视眼内结构形态学变化及对其相关因素进行分析。方法:选取2023年3月至2024年3月在我院眼科门诊就诊的高度近视患者89例175眼,正常对照组67例129眼,分别测量两组患者屈光度(D)、眼轴(AL)、眼压(IOP)、前房深度(ACD)、角膜中央厚度(CCT)及黄斑区视网膜厚度。结果:组间AL、IOP、ACD比较差异均有统计学意义(t=47.94、-7.76、18.67,均为P<0.001),组间CCT比较差异有统计学意义(t=2.45,均为P<0.05);组间M、S1-3mm、I1-3mm、N1-3mm、S3-6mm、I3-6mm、T3-6mm、N3-6mm比较差异有统计学意义(t=4.72、-3.62、2.14、-3.65、-5.73、-2.15、-3.62、-3.21,除I1-3mm、I3-6mm、N3-6mmP<0.05外,余均为P<0.001);组间T1-3mm比较差异无统计学意义(t=-1.14,P>0.05)。两组中SE与AL、ACD存在负相关关系(r=-0.99、-0.59,r=-0.69、-0.55,均为P<0.01);但与CCT无相关性(r=0.01、-0.09,均为P>0.05);AL与ACD存在正相关关系(r=0.69、0.88,均为P<0.01);IOP与CCT存在正相关关系(r=0.73、0.85,均为P<0.01)。SE与T1-3mm、I1-3mm、S1-3mm、N3-6mm、T3-6mm、I3-6mm、S3-6mm存在显著的正相关关系(r1=0.75、0.59、0.58、0.51、0.62、0.72、0.63,均为P<0.01),与M、N1-3mm无相关性(r1=0.09、0.10,P>0.05);AL与T1-3mm、I1-3mm、S1-3mm、N3-6mm、T3-6mm、I3-6mm、S3-6mm存在显著的负相关关系(r2=-0.74、-0.57、-0.55、-0.51、-0.60、-0.70、-0.61,均为P<0.01),与M、N1-3mm无相关性(r2=-0.08、-0.11,P>0.05)。结论:随屈光度的增加,AL显著延长,且伴随ACD加深;AL增加是近视发生的主要相关因素,但与CCT无相关性;高度近视患者黄斑区视网膜厚度均较正视眼组薄。早期干预可预防近视进一步发展。
文章关键词
高度近视;眼内结构形态;相关性分析
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