作者
李 俊,张方杰,陈 婧,安 玲
文章摘要
目的:分析不同年龄段腹膜透析(PD)患者的临床特点及预后。方法:选择青海省人民医院肾内科行CAPD治疗并持续至少3个月以上的ESRD患者,将其分为青年组(年龄为18-44岁),中年组(年龄为45-59岁),老年组(年龄≥60岁),通过数据分析各个年龄段CAPD患者的临床特点及影响预后的因素。结果:与青年组相比,中年组的SI、UA水平较低(P<0.05),老年组Alb水平较低(P<0.05),而GLU水平较高(P<0.05);随访1年后,与青年组相比,中年组VitB12水平较高(P<0.05),老年组SF、VitB12、GLU水平较高(P<0.05),UA、PTH、P水平较低(P<0.05);3.转归:死亡132例,转血透132例,肾移植患者33例,转出患者2例。老年组继续行CAPD患者低于青年组及中年组(P<0.05)。影响因素:低HB、低TP、低Mg是青中老年组的独立危险因素;而低HB、低TP、低Mg也是汉族组独立危险因素。结论:1.青年组中低血红蛋白和高血磷显著增加CAPD患者预后死亡风险;老年组中总蛋白水平是CAPD患者预后关键的独立保护因素。3.血红蛋白、白蛋白及总蛋白水平是CAPD患者预后生存的强预测因子,低水平与死亡风险显著相关。
文章关键词
腹膜透析;年龄;危险因素
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