胡 蝶,张广玉

阿尔茨海默病（AD）是影响全球数百万人的最普遍的神经退行性疾病之一，患病率和发病率都随着年龄的增长而增加。它的特征是认知能力下降，特别是与胆碱能神经元的退化有关。AD是痴呆症最常见的原因，是一个日益严重的全球健康问题，对个人和社会具有巨大影响。在本综述总结了目前对AD发病机制和最新治疗的理解，以期为未来开发新的治疗策略提供新的思路。

阿尔茨海默病；发病机制；治疗

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