程 雪,唐东昕

大肠癌作为常见的消化道恶性肿瘤，而肝脏作为大肠癌最常见的转移部位，半数以上大肠癌患者在死亡时存在着肝转移。肠道和肝脏经胆管、门静脉和体循环协同作用、双向交流，形成肠肝轴，而肠肝轴是大肠癌肝转移的发病机制，肠道菌群与胆汁酸的协同造成大肠癌肝转移的重要因素。中医药防治大肠癌肝转移，是在肠肝轴基础上，针对精血、胆汁与肠肝轴间紧密关系进行防治，辨明大肠癌肝转移内在机理，灵活运用中医药，切实体现中医药诊疗大肠癌肝转移的优势，提供了一定新的思路。

肠肝轴；大肠癌肝转移；肠道菌群；中医药防治

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