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目的：通过评估手术持续时间、伤口闭合和并发症发生率，评价并比较使用25G或27G器械进行玻璃体切除术进行黄斑前膜手术的有效性。研究方法：在这项回顾性病历分析中，我们分析了50例25G和50例27G玻璃体切除术治疗视网膜前膜的术中和术后即刻情况。结果如下：两组的基线特征无统计学差异。25G组的玻璃体切除时间略长于27G组，但差异无统计学意义（P=0.06）。术中剥膜时间，两组无明显差异（P=0.08）。两组在伤口闭合时间上有差异，25G穿刺口闭合时间长与27G刺口闭合时间（P=0.02)。结论：研究结果表明，27G玻璃体切除术是一种安全、有效的黄斑手术，是常用的25G玻璃体切除术的替代方法。27G玻璃体切除术需要较少的操作来实现伤口闭合。27G玻璃体切除术与25G玻璃体切除术相比，不会增加黄斑前膜手术的手术时间或并发症。

25G玻璃体切割术；27G玻璃体切割术；视网膜前膜

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