赵铭桢,张庆欣

血管周围间隙（Perivascular Spaces，PVS）是神经系统内的正常解剖结构，是蛛网膜下隙围绕脑内血管壁形成的间隙，表面覆盖软脑膜。PVS一般大小在2mm以内，当超过2mm时，认为PVS扩大，即血管周围间隙扩大(Enlarged Perivascular Spaces，EPVS)，这也是影像和临床目前共同的一个诊断标准。随着年龄的增长或者疾病的炎性沉积物，致使脑内的淋巴循环受阻，从而出现EPVS。本文通过对EPVS的影像表现、关于EPVS的新型影像技术、EPVS相关的临床危险因素及一些特殊临床疾病这些方面进行综述，从而全面掌握EPVS，更好的推动以后对EPVS的相关研究。

血管周围间隙扩大；磁共振；危险因素；临床疾病

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